Comorbidities in Cystic Fibrosis
LESSON 1: HAEMOPTYSIS
Button BM, Wilson C, Dentice R, Cox N, Middleton A, Tannenbaum E, Bishop J, Cobb R, Burton K, Wood M, Moran F, Black R, Bowen S, Day R, Depiazzi J, Doiron K, Doumit M, Dwyer T, Elliot A, Fuller L, Hall K, Hutchins M, Kerr M, Lee A, Mans C, O’Connor L, Steward R, Potter A, Rasekaba T, Scoones R, Tarrant B, Ward N, West S, White D, Wilson L, Wood J, Holland AE. Physiotherapy for Cystic Fibrosis in Australia and New Zealand: A Clinical Practice Guideline. Respirology2016; 21: 656–667
Flume PA, Mogayzel PJ, Robinson KA, et al. Cystic Fibrosis Pulmonary Guidelines: Pulmonary Complications: Hemoptysis and Pneumothorax. Am J Respir Crit Care Med. 2010 Aug 1;182(3):298-306. Paediatric Respiratory Reviews 2012 (13) 200 – 205.
Standards of Care and Good Clinical Practice for the Physiotherapy Management of Cystic Fibrosis. Third Edition April 2017 https://www.cysticfibrosis.org.uk/
https://www.cff.org/CF-Community-Blog/Posts/2017/Setting-the-Record-Straight-About-Coughing-Up-Blood/
http://www.torontoadultcf.com/cf-information/hemoptysis-0
LESSON 2: PNEUMOTHORAX
Button BM, Wilson C, Dentice R, Cox N, Middleton A, Tannenbaum E, Bishop J, Cobb R, Burton K, Wood M, Moran F, Black R, Bowen S, Day R, Depiazzi J, Doiron K, Doumit M, Dwyer T, Elliot A, Fuller L, Hall K, Hutchins M, Kerr M, Lee A, Mans C, O’Connor L, Steward R, Potter A, Rasekaba T, Scoones R, Tarrant B, Ward N, West S, White D, Wilson L, Wood J, Holland AE. Physiotherapy for Cystic Fibrosis in Australia and New Zealand: A Clinical Practice Guideline. Respirology2016; 21: 656–667
Flume PA, Mogayzel PJ, Robinson KA, et al. Cystic Fibrosis Pulmonary Guidelines: Pulmonary Complications: Hemoptysis and Pneumothorax. Am J Respir Crit Care Med. 2010 Aug 1;182(3):298-306. Paediatric Respiratory Reviews 2012 (13) 200 – 205.
Standards of Care and Good Clinical Practice for the Physiotherapy Management of Cystic Fibrosis. Third Edition April 2017 https://www.cysticfibrosis.org.uk/
LESSON 3: URINARY STRESS INCONTINENCE
Button BM, Wilson C, Dentice R, Cox N, Middleton A, Tannenbaum E, Bishop J, Cobb R, Burton K, Wood M, Moran F, Black R, Bowen S, Day R, Depiazzi J, Doiron K, Doumit M, Dwyer T, Elliot A, Fuller L, Hall K, Hutchins M, Kerr M, Lee A, Mans C, O’Connor L, Steward R, Potter A, Rasekaba T, Scoones R, Tarrant B, Ward N, West S, White D, Wilson L, Wood J, Holland AE. Physiotherapy for Cystic Fibrosis in Australia and New Zealand: A Clinical Practice Guideline. Respirology2016; 21: 656–667
Faulkner, J., A. Gates, W. G. Flight, M. Bulpett, B. Reade, J. Hobbs and A. Midwinter (2022). Impact of triple CFTR modulator therapy on urinary incontinence symptoms in adults with cystic fibrosis.” Journal of Cystic Fibrosis 21(Suppl 20):WS10.03.
McVean R, Orr A, Webb AK, Bradbury A, Kay L, Phillips E, Dodd ME. Treatment of urinary incontinence in cystic fibrosis. Journal of Cystic Fibrosis 2003;4: 171-176
Standards of Care and Good Clinical Practice for the Physiotherapy Management of Cystic Fibrosis. Third Edition April 2017 https://www.cysticfibrosis.org.uk/
LESSON 4: LIVER DISEASE
Colombo C, Crosignani A, Battezzati PM. Liver involvement in cystic fibrosis. J Hepatol 1999; 31: 946-954
Desai CS et al. Survival of cystic fibrosis patients undergoing liver and liver-lung transplantations. Transplantation proceedings. 2013; vol.45, no.1, p.290-292.
Moyer K, Balistreri W. Hepatobiliary disease in patients with cystic fibrosis. Curr Opin Gastroenterol. 2009;25(3):272-8.
Parisi GF et al. Liver disease in cystic fibrosis: an update. Hepatitis monthly. 2013; 13; 8, p 1735-1743
LESSON 5: PREGNANCY IN CF
Ahluwalia M, Hong J, Hadeh A, Ferrin M, Hadjiliadis D. Cystic Fibrosis and pregnancy in the modern era: A case control study. Journal of Cystic Fibrosis. 2014. 13.69-73
Button, B. M., Wilson, C., Dentice, R., Cox, N. S., Middleton, A., Tannenbaum, E., Bishop, J., Cobb, R., Burton, K., Wood, M., Moran, F., Black, R., Bowen, S., Day, R., Depiazzi, J., Doiron, K., Doumit, M., Dwyer, T., Elliot, A., Fuller, L., Hall, K., Hutchins, M., Kerr, M., Lee, A. L., Mans, C., O’Connor, L.,Steward, R., Potter, A., Rasekaba, T., Scoones, R., Tarrant, B., Ward, N., West, S., White, D.,Wilson, L., Wood, J., and Holland, A. E. (2016) Physiotherapy for cystic fibrosis in Australia and New Zealand: A clinical practice guideline. Respirology, 21: 656–667.
Edenborough F, Borgo G, Knoop C, Lannerfors L, Mackenzie W, Madge S, Morton A, Oxley H, Touw D, Benham M, Johannesson M. Guidelines for management of pregnancy in women with cystic Fibrosis. Journal of Cystic Fibrosis. 2008. 7: S2-S32.
Grigoriadis C, Tympa A, Theodoraki K. Cystic Fibrosis and preganancy counselling, obstetrical management and prenatal outcomes. Invest Clin. 2015. 56(1). 66-73
Johannesson M. Effects of pregnancy on health: certain aspects of importance for women with CF. Journal of Cystic Fibrosis. 2002. 1: 9-12.
LESSON 6: CYSTIC FIBROSIS RELATED DIABETES
Brunzell C, hardin D, Kogler A, Moran A, Schindler T. Managing CFRD.Cystic Fibrosis Foundation Guidelines.2015.
Button, B. M., Wilson, C., Dentice, R., Cox, N. S., Middleton, A., Tannenbaum, E., Bishop, J., Cobb, R., Burton, K., Wood, M., Moran, F., Black, R., Bowen, S., Day, R., Depiazzi, J., Doiron, K., Doumit, M., Dwyer, T., Elliot, A., Fuller, L., Hall, K., Hutchins, M., Kerr, M., Lee, A. L., Mans, C., O’Connor, L.,Steward, R., Potter, A., Rasekaba, T., Scoones, R., Tarrant, B., Ward, N., West, S., White, D.,Wilson, L., Wood, J., and Holland, A. E. (2016) Physiotherapy for cystic fibrosis in Australia and New Zealand: A clinical practice guideline. Respirology, 21: 656–667.
Middleton P, Wagenaar M, Matson A, Craig M, Holmes-Walker D, Katz T, Hameed S. Australian standards of care for CFRD. Respirology. 2014. 19: 185-192.
Moran A, Brunzell C, Cohen RC, Katz M, Marshall BC, Onady G, Robinson KA, Sabadosa KA, Stecenko A, Slovis B. Clinical care guidelines for cystic fibrosis-related diabetes: a position statement of the American Diabetes Association and a clinical practice guideline of the Cystic Fibrosis Foundation, endorsed by the Pediatric Endocrine Society. Diabetes Care. 2010; 33: 2697-708
https://www.cff.org/Life-With-CF/Daily-Life/Cystic-Fibrosis-related-Diabetes/Managing-CFRD.pdf
LESSON 7: CYSTIC FIBROSIS BONE DISEASE
Buntain HM, Greer RM, Schluter PJ, Wong JC, Batch JA, Potter JM, Lewindon PJ, Powell E, Wainwright CE, Bell SC. Bone mineral density in Australian children, adolescents and adults with cystic fibrosis: a controlled cross sectional study. Thorax. 2004; 59: 149-55.
Button, B. M., Wilson, C., Dentice, R., Cox, N. S., Middleton, A., Tannenbaum, E., Bishop, J., Cobb, R., Burton, K., Wood, M., Moran, F., Black, R., Bowen, S., Day, R., Depiazzi, J., Doiron, K., Doumit, M., Dwyer, T., Elliot, A., Fuller, L., Hall, K., Hutchins, M., Kerr, M., Lee, A. L., Mans, C., O’Connor, L.,Steward, R., Potter, A., Rasekaba, T., Scoones, R., Tarrant, B., Ward, N., West, S., White, D.,Wilson, L., Wood, J., and Holland, A. E. (2016) Physiotherapy for cystic fibrosis in Australia and New Zealand: A clinical practice guideline. Respirology, 21: 656–667
Grey V, Atkinson S, Drury D, Casey L, Ferland G, Gundberg C, Lands LC. Prevalence of low bone mass and deficiencies of vitamins D and K in pediatric patients with cystic fibrosis from 3 Canadian centers. Pediatrics. 2008; 122: 1014-20
Haworth CS. Impact of cystic fibrosis on bone health. Current opinion in pulmonary medicine. 2010; 16: 616-22
Hind K, Truscott JG, Conway SP. Exercise during childhood and adolescence: a prophylaxis against cystic fibrosis-related low bone mineral density? Exercise for bone health in children with cystic fibrosis. Journal of Cystic Fibrosis. 2008; 7: 270-6
Tejero Garcia S, Giraldez Sanchez MA, Cejudo P, Quintana Gallego E, Dapena J, Garcia Jimenez R, Cano Luis P, Gomez de Terreros I. Bone health, daily physical activity, and exercise tolerance in patients with cystic fibrosis. Chest. 2011; 140: 475-81
LESSON 8: Excessive and Ineffective Coughing
Anstead M, Saiman L, Mayer-Hamblett N, Lands LC, Kloster M, Goss CH, Rose L, Burns JL, Marshall B, Ratjen F. Pulmonary exacerbations in CF patients with early lung disease. J Cyst Fibros. 2014 Jan;13(1):74-9. doi: 10.1016/j.jcf.2013.07.006. Epub 2013 Sep 10. PMID: 24029220.
Fathi H, Moon T, Donaldson J, Jackson W, Sedman P, Morice AH. Cough in adult cystic fibrosis: diagnosis and response to fundoplication. Cough. 2009 Jan 18;5:1. doi: 10.1186/1745-9974-5-1. PMID: 19149907; PMCID: PMC2634760.
Kerem E, Wilschanski M, Miller NL, Pugatsch T, Cohen T, Blau H, Rivlin J, Shoseyov D, Reha A, Constantine S, Ajayi T, Hirawat S, Elfring GL, Peltz SW, Miller LL. Ambulatory quantitative waking and sleeping cough assessment in patients with cystic fibrosis. J Cyst Fibros. 2011 May;10(3):193-200. doi: 10.1016/j.jcf.2011.02.003. Epub 2011 Apr 2. PMID: 21459051.
